ADA3-containing complexes associate with estrogen receptor alpha
نویسندگان
چکیده
منابع مشابه
ADA3-containing complexes associate with estrogen receptor alpha.
Transcriptional repression and activation by nuclear receptors (NRs) are brought about by coregulator complexes. These complexes modify the chromatin environment of target genes and affect the activity of the basal transcription machinery. We have previously implicated the yeast ADA3 protein in transcriptional activation by estrogen and retinoid X receptors in yeast and mammalian cells. Here we...
متن کاملOverexpression of Endometrial Estrogen Receptor-Alpha in The Window of Implantation in Women with Unexplained Infertility
Objective Background: Failure in the endometrial receptivity may account for a significant number of infertility cases including unexplained infertility in women. Reduction in the endometrial estrogen receptor-alpha (ER-α) expression during window of implantation may be a critical event that coincides with expression of specific genes and providing a receptive endometrium. The aim of present st...
متن کاملpromoter hypermethylation of estrogen receptor alpha gene is correlated to estrogen receptor negativity in iranian patients with sporadic breast cancer
objective: breast cancer is the most common cancer in iranian women. breast tumors are classified based on the estrogen receptor alpha (erα) expression status into er negative and er positive tumors. er negative tumors tend to have worse prognosis and less likely to respond to endocrine therapy. aberrant methylation of gene promoter is one of the mechanisms for gene silencing in breast tumors. ...
متن کاملEstrogen-related Receptor and Estrogen-related Receptor Associate with Unfavorable and Favorable Biomarkers, Respectively, in Human Breast Cancer
The importance of estrogen-related receptors (ERRs) in human breast cancer was assessed by comparing their mRNA profiles with established clinicopathological indicators and mRNA profiles of estrogen receptors (ERs) and ErbB family members. Using real-time quantitative PCR assays, mRNA levels of ER , ER , epidermal growth factor receptor, ErbB2, ErbB3, ErbB4, ERR , ERR , and ERR were determined ...
متن کاملLabel-free detection of anti-estrogen receptor alpha and its binding with estrogen receptor peptide alpha by terahertz spectroscopy
Terahertz (THz) spectroscopic techniques were employed to study the hydration shell formation around anti-estrogen receptor alpha (AER-a), an important biomarker in breast cancer diagnosis, and to detect the binding reaction between AER-a and estrogen receptor peptide alpha (ERP-a), in aqueous solutions. A remarkable nonlinear relation between THz absorption and AER-a concentration was demonstr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2002
ISSN: 1362-4962
DOI: 10.1093/nar/30.11.2508